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Report on application of biological active food additive "REKITSEN -RD" in complex treatment of patients with tuberculosis

версия для печати

  1. Purpose of research
    The work was carried out to study the efficiency of REKITSEN - RD in clinical application at hospital patients with a tuberculosis.
  2. Patients
    REKITSEN - RD was administrated for the treatment of patients with marked symptoms of an intoxication and negative consequences of anti-tuberculosis therapy: neurotoxic, hepatotoxic, cardiotoxic reactions, dyspepsia, dysbacteriosis, and growth of pathogenic fungi and other side effects.
  3. Methods
    Efficiency of the treatment was assessed by comparing the degree and time decreases in biochemical parameters and clinical symptoms in group of patients with REKITSEN -- RD administration and in placebo group.
  4. Application of "REKITSEN - RD":
    1 table spoon of REKITSEN - RD 3-4 times a day 30 minutes before a meal during 4 weeks.

RESULTS:

REKITSEN - RD was applied in complex therapy to 23 patients with tuberculosis.

7 persons with accompanying gastrointestinal disorders (ch. colitis; ch. pancreatitis; ch. hepatites; ch. cholecystitis; biliary dyskinesia; ulcer disease). 16 persons with side effects to anti-tuberculosis therapy:

  • 10 persons with hepatotoxic reaction to isoniazid and rifampicin;
  • 2 persons with dyspepsia to pirazinamid and ethionamid;
  • 4 persons with dysbacteriosis to rifampicin and tarivid administration

Application of REKITSEN - RD to patients with accompanying gastrointestinal disorders allowed to administering of specific therapy in full, moreover during REKITSEN RD application general physical and mental states of patients were improved; ACT, ALT did not increase; dyspepsia phenomenon disappeared.

In group of patients with side effects to anti-tuberculosis therapy during REKITSEN - RD administration the clinical improvement was manifested in 2-3 days, also the significant decrease in ACT, ALT was faster in comparison with the placebo group.

After the termination of REKITSEN - - RD administration the dyspepsia phenomena and ТА increases were not marked during the course of anti-tuberculosis therapy.

The reduction in intoxication during the anti-tuberculosis therapy was also investigated in patients with extensive damage of lung. In group of patients with REKITSEN RD administration the symptoms of intoxication was reduced faster in comparison with the placebo group. Taking into account the adsorptive properties of REKITSEN — RD in 2 patients with a pneumonia, REKITSEN - RD has been included in complex therapy.

Symptoms of intoxication were reduced in 4-5 days, the parameters of blood were normalized in 7-10 days.

CONCLUSIONS:

Application of a biological active food additive REKITSEN -RD in complex therapy of tuberculosis is one of promising directions in the treatment of tuberculosis for the reduction of intoxication and side effects during anti-tuberculosis therapy, the prevention of Micobacterium tuberculosis drug-resistance development.

Relatively low price of REKITSEN -- RD allows to apply it widely under present economic conditions for the treatment of poor patients with tuberculosis.

Main non-staff phthisiologist of Kirov region B.L. Motovilova
Report is compiled by Head of diagnostic department of regional clinical anti-tuberculosis dispensary, Kirov E.A.Dejnichenko

 

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